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Test Code ACTSAL Acetaminophen/Salicylate, LAB2261

Performing Laboratory

St. Luke's Hospital Cedar Rapids

Specimen Requirements

Container/Tube:

Preferred: Green-top (sodium or lithium heparin gel)

Acceptable: Gold-top serum gel tube or plain red-top tube

Specimen Volume: 0.2 mL of plasma or serum

Stability: Acetaminophen- 2 hours

                       Salicylate- Separated specimens should be analyzed immediately or kept at

                                    room temperature for 7 days or 2 – 8 °C and analyzed within 2 weeks.

                                    For longer storage, samples may be frozen at -20 °C for up to 6 months.

Collection Instructions: Acetaminophen- Peak levels occur within 30-60 minutes after an oral dose .

                                               Salicylate- Peak levels occur 1 – 2 hours after a dose, depending on the drug       

                                                               formulation.

 

Reference Values

Acetaminophen- Therapeutic range: 10-20 mcg/mL

                                Critical Value: ≥ 150.0 mcg/mL

 

Salicylate- Analgesic therapeutic range: 2-10 mg/dL

                    Antiarthritic therapeutic range: 15-30 mg/dL

                    Critical Value: >30 mg/dL

Useful For

Acetaminophen (brand name: Tylenol®) levels are measured to determine concentrations in the blood stream.  This can be of extreme importance in cases of suspected intoxication because effective antidotes are available.

 

Salicylate measurements are used in the diagnosis and treatment of salicylate overdose and in monitoring salicylate levels to insure appropriate therapy.

 

 

Day(s) Test Set Up

Monday through Sunday

Methodology

Colorimetric

Testing Classification and CPT Coding

80329