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Test Code AMIODM Amiodarone, Serum

Additional Codes

 

MAYO Test ID

AMIO

EPIC Test ID

LAB567

 

Reporting Name

Amiodarone, S

Useful For

Monitoring amiodarone therapy, especially when amiodarone is coadministered with other drugs that may interact

 

Evaluation of possible amiodarone toxicity

 

Assessment of patient compliance

Method Name

High-Turbulence Liquid Chromatography Mass Spectrometry (HTLC-MS/MS)

Performing Laboratory

Mayo Medical Laboratories in Rochester

Specimen Type

Serum Red


Specimen Required


Collection Container/Tube: Red top

Submission Container/Tube: Plastic vial

Specimen Volume: 3 mL

Collection Instructions: Draw blood no sooner than 12 hours (trough value) after last dose.


Specimen Minimum Volume

0.5 mL

Specimen Stability Information

Specimen Type Temperature Time
Serum Red Frozen (preferred) 14 days
  Refrigerated  72 hours
  Ambient  24 hours

Reject Due To

Hemolysis

Mild OK; Gross OK

Lipemia

Mild OK; Gross OK

Icterus

Mild OK; Gross OK

Other

Serum gel tube

Reference Values

AMIODARONE

Therapeutic concentration: 0.5-2.0 mcg/mL

Toxic concentration: >2.5 mcg/mL

 

DESETHYLAMIODARONE

No therapeutic range established; activity and serum concentration are similar to parent drug.

Day(s) and Time(s) Performed

Tuesday through Saturday; 12 a.m.

Saturday; 4 p.m.

CPT Code Information

80299

LOINC Code Information

Test ID Test Order Name Order LOINC Value
AMIO Amiodarone, S 55152-3

 

Result ID Test Result Name Result LOINC Value
9247 Amiodarone, S 3330-8
2485 Desethylamiodarone 6774-4

Analytic Time

2 days

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.