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Test Code AT3AGM Antithrombin Antigen, Plasma

Additional Codes

 

MAYO Test ID

ATTI

EPIC Test ID

LAB759

 

Reporting Name

Antithrombin Antigen, P

Useful For

Assessing abnormal results of the antithrombin activity assay (ATTF / Antithrombin Activity, Plasma), which is recommended as the primary (screening) antithrombin assay

 

Diagnosing antithrombin deficiency, acquired or congenital, in conjunction with measurement of antithrombin activity

 

As an adjunct in the diagnosis and management of carbohydrate-deficient glycoprotein syndromes

Performing Laboratory

Mayo Medical Laboratories in Rochester

Specimen Type

Plasma Na Cit


Advisory Information


Coagulation testing is highly complex, often requiring the performance of multiple assays and correlation with clinical information. For that reason, we suggest ordering THRMP / Thrombophilia Profile.



Specimen Required


See Coagulation Studies in Special Instructions.

 

Patient Preparation: Heparin treatment may lower plasma antithrombin. 

Specimen Type: Platelet-poor plasma

Collection Container/Tube: Light-blue top (citrate)

Submission Container/Tube: Polypropylene vial

Specimen Volume: 1 mL

Collection Instructions:

1. Spin down, remove plasma, and spin plasma again.

2. Freeze specimen immediately at ≤-40° C, if possible.

Additional Information:

1. Double-centrifuged specimen is critical for accurate results as platelet contamination may cause spurious results.

2. Each coagulation assay requested should have its own vial.


Specimen Minimum Volume

0.5 mL

Specimen Stability Information

Specimen Type Temperature Time
Plasma Na Cit Frozen 14 days

Special Instructions

Reference Values

Adults: 80-120%

Normal, full-term newborn infants may have decreased levels (≥35-40%) which reach adult levels by 180 days postnatal.*

Healthy, premature infants (30-36 weeks gestation) may have decreased levels which reach adult levels by 180 days postnatal.*

*See Pediatric Hemostasis References in Coagulation Studies in Special Instructions.

Day(s) and Time(s) Performed

Monday through Friday

Test Classification

This test has been modified from the manufacturer's instructions. Its performance characteristics were determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.

CPT Code Information

85301

LOINC Code Information

Test ID Test Order Name Order LOINC Value
ATTI Antithrombin Antigen, P 27812-7

 

Result ID Test Result Name Result LOINC Value
ATTI Antithrombin Antigen, P 27812-7

Analytic Time

2 hours

Reject Due To

Hemolysis

Mild OK; Gross reject

Lipemia

Mild OK; Gross reject

Icterus

Mild OK; Gross reject

Other

NA

Method Name

Automated Latex Immunoassay (LIA)

Forms

If not ordering electronically, complete, print, and send a Coagulation Test Request Form (T753) with the specimen (http://www.mayomedicallaboratories.com/it-mmfiles/coagulation-test-request-form.pdf)