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Test Code BAPS Bile Acid Profile, Serum


Specimen Required


Patient Preparation: Patient must be fasting for 12 to 14 hours.

Collection Container/Tube:

Preferred: Red top

Acceptable: Serum gel

Submission Container/Tube: Plastic vial

Specimen Volume: 0.5 mL


Useful For

Evaluating the enterohepotic cycle consisting of the biliary system, intestine, portal circulation, and hepatocytes

 

Researcher in need of free and conjugated values of all 20 bile acid species as well as total bile acid

Method Name

Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)

Reporting Name

Bile Acid Profile, S

Specimen Type

Serum

Specimen Minimum Volume

0.3 mL

Specimen Stability Information

Specimen Type Temperature Time
Serum Refrigerated (preferred) 90 days
  Ambient  90 days
  Frozen  90 days

Reject Due To

Hemolysis

Mild OK; Gross OK

Lipemia

Mild OK; Gross OK

Icterus

NA

Other

Nonfasting specimen or plasma

Reference Values

Analyte

Normal (nmol/mL)

Chenodeoxycholic acid

≤2.26

Cholic acid

≤2.74

Deoxycholic acid

≤2.84

Dihydroxycholestanoic acid

≤0.07

Glycochenodeoxycholic acid

≤5.14

Glycocholic acid

≤2.17

Glycodeoxycholic acid

≤3.88

Glycohyodeoxycholic acid

≤0.01

Glycolithocholic acid

≤0.11

Glycoursodeoxycholic acid

≤1.00

Hyodeoxycholic acid

≤0.12

Lithocholic acid

≤0.09

Taurochenodeoxycholic acid

≤0.80

Taurocholic acid

≤0.31

Taurodeoxycholic acid

≤0.78

Taurohyodeoxycholic acid

≤0.02

Taurolithocholic acid

≤0.04

Tauroursodeoxycholic acid

≤0.05

Trihydroxycholestanoic acid

≤1.73

Ursodeoxycholic acid

≤0.64

Total bile acids

≤19.00

Day(s) and Time(s) Performed

Monday through Friday; 8 a.m.

Analytic Time

2 days (not reported on Saturday or Sunday)

Performing Laboratory

Mayo Medical Laboratories in Rochester

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.

CPT Code Information

82542

LOINC Code Information

Test ID Test Order Name Order LOINC Value
BAPS Bile Acid Profile, S In Process

 

Result ID Test Result Name Result LOINC Value
35802 Chenodeoxycholic acid In Process
35801 Cholic acid In Process
35803 Deoxycholic acid In Process
35819 Dihydroxycholestanoic acid In Process
35808 Glycochenodeoxycholic acid In Process
35807 Glycocholic acid In Process
35809 Glycodeoxycholic acid In Process
35811 Glycohyodeoxycholic acid In Process
35812 Glycolithocholic acid In Process
35810 Glycoursodeoxycholic acid In Process
35805 Hyodeoxycholic acid In Process
35806 Lithocholic acid In Process
35814 Taurochenodeoxycholic acid In Process
35813 Taurocholic acid In Process
35815 Taurodeoxycholic acid In Process
35817 Taurohyodeoxycholic acid In Process
35818 Taurolithocholic acid In Process
35816 Tauroursodeoxycholic acid In Process
35820 Trihydroxycholestanoic acid In Process
35804 Ursodeoxycholic acid In Process
35821 Total bile acids In Process