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Test Code BENZUM Benzodiazepines Confirmation, Urine

Important Note

This test is for confirmation testing only. For screening purposes please order a Rapid Drug Screen, Urine LAB676 first before this test.

Additional Codes

 

MAYO Test ID

BENZU

EPIC Test ID

LAB5349

 

Reporting Name

Benzodiazepines Confirmation, U

Useful For

Detecting drug use involving benzodiazepines such as alprazolam, flunitrazepam, chlordiazepoxide, diazepam, flurazepam, lorazepam, and triazolam

Performing Laboratory

Mayo Medical Laboratories in Rochester

Specimen Type

Urine


Advisory Information


For situations where chain of custody is required, a Chain-of-Custody Kit (T282) is available. For chain-of-custody testing, order BENZX / Benzodiazepines Confirmation, Chain of Custody, Urine.

Additional Testing Requirements


If urine creatinine is required or adulteration of the sample is suspected, the following test should be requested, ADULT / Adulterants Survey, Urine. For additional information, refer to ADULT / Adulterants Survey, Urine.



Specimen Required


Container/Tube: Plastic, 60-mL urine bottle

Specimen Volume: 20 mL

Collection Instructions:

1. Collect a random urine specimen.

2. No preservative.

Additional Information:

1. No specimen substitutions.

2. No STATS are accepted for this procedure.

3. Additional drug panels and specific requests are available. Call Mayo Medical Laboratories at 800-533-1710 or 507-266-5700.

4. Submitting less than 20 mL will compromise our ability to perform all necessary testing.


Specimen Minimum Volume

5 mL

Specimen Stability Information

Specimen Type Temperature Time
Urine Refrigerated (preferred) 14 days
  Frozen  14 days
  Ambient  72 hours

Reference Values

Negative

 

Cutoff concentrations:

NORDIAZEPAM BY GC-MS

<100 ng/mL

 

OXAZEPAM BY GC-MS

<100 ng/mL

 

LORAZEPAM BY GC-MS

<100 ng/mL

 

TEMAZEPAM BY GC-MS

<100 ng/mL

 

OH-ETHYL-FLURAZEPAM BY GC-MS

<100 ng/mL

 

7-NH-CLONAZEPAM BY GC-MS

<100 ng/mL

 

ALPHA OH-ALPRAZOLAM BY GC-MS

<100 ng/mL

 

7-NH-FLUNITRAZEPAM BY GC-MS

<50 ng/mL

 

ALPHA OH-TRIAZOLAM BY GC-MS

<100 ng/mL

Day(s) and Time(s) Performed

Monday through Friday

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.

CPT Code Information

80346

G0480 (if appropriate)

LOINC Code Information

Test ID Test Order Name Order LOINC Value
BENZU Benzodiazepines Confirmation, U In Process

 

Result ID Test Result Name Result LOINC Value
21441 Nordiazepam-by GC/MS 16228-9
20655 Oxazepam-by GC/MS 16201-6
20656 Lorazepam-by GC/MS 17088-6
20657 Temazepam-by GC/MS 20559-1
20658 OH-Ethyl-Flurazepam-by GC/MS 20532-8
20659 7-NH-Clonazepam-by GC/MS 51776-3
20670 Alpha OH-Alprazolam-by GC/MS 16348-5
20660 7-NH-Flunitrazepam-by GC/MS 51777-1
20661 Alpha OH-Triazolam-by GC/MS 49876-6
20663 Benzodiazepines Interpretation 69050-3
20664 Chain of Custody No LOINC Needed

Analytic Time

2 days

Reject Due To

Hemolysis

Mild OK; Gross OK

Lipemia

NA

Icterus

Mild OK; Gross OK

Other

NA

Method Name

Gas Chromatography-Mass Spectrometry (GC-MS) Confirmation with Quantitation

Forms

Chain-of-Custody Request Form is included in the Chain-of-Custody Kit (T282). A copy of this form is also available at http://www.mayomedicallaboratories.com/it-mmfiles/chain-of-custody-request-form.pdf.