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Test Code BILEB Bile Acids, Total, Serum

Additional Codes







Useful For

An aid in the evaluation of liver function


Evaluation of liver function changes before the formation of more advanced clinical signs of illness such as icterus


An aid in the determination of hepatic dysfunction as a result of chemical and environmental injury


An indicator of hepatic histological improvement in chronic hepatitis C patients responding to interferon treatment


An indicator for intrahepatic cholestasis of pregnancy

Method Name


Reporting Name

Bile Acids, Total, S

Specimen Type


Advisory Information

This test is for evaluation of hepatobiliary dysfunction.


For evaluation of bowel dysfunction, order BA48F / Bile Acids, Fractionated and Total, 48 Hour, Feces.

For evaluation of patients treated with urso or cholate, order BAFS / Bile Acids, Fractionated and Total, Serum.

For evaluation of inborn errors of metabolism, order BAIPD / Bile Acids for Peroxisomal Disorders, Serum.

Specimen Required

Patient Preparation:

1. Fasting, 8-hour minimum.

2. Do not order in patients receiving bile acid therapy.


Preferred: Serum gel

Acceptable: Red top

Submission Container/Tube: Plastic vial

Specimen Volume: 0.5 mL

Collection Instructions:

1. Serum gel tubes should be centrifuged within 2 hours of collection.

2. Red-top tubes should be centrifuged and aliquoted within 2 hours of collection.

3. See Bile Acid-Associated Tests Ordering Guide in Special Instructions.

Specimen Minimum Volume

0.25 mL

Specimen Stability Information

Specimen Type Temperature Time
Serum Refrigerated (preferred) 7 days
  Frozen  30 days
  Ambient  24 hours

Reject Due To


Mild OK; Gross reject


Mild OK; Gross OK


Mild OK; Gross reject



Reference Values

≤10 mcmol/L

Day(s) and Time(s) Performed

Monday through Sunday; Continuously

Analytic Time

Same day/ 1 day

Performing Laboratory

Mayo Medical Laboratories in Rochester

Test Classification

This test has been cleared or approved by the U.S. Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.

CPT Code Information



LOINC Code Information

Test ID Test Order Name Order LOINC Value
BILEA Bile Acids, Total, S 14628-2


Result ID Test Result Name Result LOINC Value
BILEA Bile Acids, Total, S 14628-2