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Test Code CLYME Lyme Disease Serology, Spinal Fluid

Reporting Name

Lyme Disease Serology, CSF

Useful For

Aiding in the diagnosis of Lyme neuroborreliosis

Reflex Tests

Test ID Reporting Name Available Separately Always Performed
CLYWB Lyme Disease Ab, Immunoblot, CSF Yes No

Testing Algorithm

If Lyme disease serology is positive, then immunoblot testing will be performed at an additional charge.


See Acute Tick-Borne Disease Testing Algorithm in Special Instructions.

Method Name

Enzyme-Linked Immunosorbent Assay (ELISA)

Performing Laboratory

Mayo Medical Laboratories in Rochester

Specimen Type


Specimen Required

Collection Container/Tube: Sterile vial

Submission Container/Tube: Plastic vial

Specimen Volume: 1 mL

Additional Information: This test is not available for specimens originating in New York.

Specimen Minimum Volume

0.5 mL

Specimen Stability Information

Specimen Type Temperature Time
CSF Refrigerated (preferred) 14 days
  Frozen  14 days

Reject Due To


Mild OK; Gross OK


Mild OK; Gross OK





Reference Values


Reference values apply to all ages.

Day(s) and Time(s) Performed

Monday through Friday; 10 a.m.

CPT Code Information

86618-Lyme disease serology

86617 x 2-Lyme blot (if appropriate)

LOINC Code Information

Test ID Test Order Name Order LOINC Value
CLYME Lyme Disease Serology, CSF 16475-6


Result ID Test Result Name Result LOINC Value
CLYME Lyme Disease Serology, CSF 16475-6

Analytic Time

Same day/1 day

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.