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Test Code DHEASI Dehydroepiandrosterone Sulfate (DHEA-S), Plasma or Serum, LAB524

Additional Codes




Immunoenzymatic Chemiluminescent Assay

Performing Laboratory

St. Luke's Hospital Laboratory, Cedar Rapids

Specimen Requirements


Preferred:  Gold-top serum gel tube

Acceptable: Red-top serum tube, Lavender-top (EDTA) tube(s) or green-top (lithium or sodium heparin) tube
Specimen: 0.5 mL of serum or plasma

Stability(when removed from cells):

  • Room Temperature:  4 hours
  • Refrigerated:  6 days
  • Frozen:  Undetermined

Transport Temperature: Refrigerate


Note:  This assay is affected by biotin interference.


Reference Values



26 – 460 µg/dL


35 – 569 µg/dL


Day(s) Test Set Up

Tuesday and Friday

STAT testing available Monday through Friday, day shift only

Test Classification and CPT Coding


Useful For

Measurement of circulating levels of Dehydroepiandrosterone sulfate (DHEAS), an adrenal steroid, is important in investigations of abnormal hair growth (hirsutism) and balding (alopecia) in women.  It is also of value in the assessment of adrenarche and delayed puberty.  DHEAS in circulation originates almost entirely from the adrenals, though in men some may also derive from the testes.  Although DHEAS is weakly androgenic, it can metabolize to more potent androgens like androstenedione and testosterone, and thus be an indirect cause of hirsutism or virilization.