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Test Code F2M Coagulation Factor II Activity Assay, Plasma

Additional Codes

 

MAYO Test ID

F_2

EPIC Test ID

LAB303

 

Reporting Name

Coag Factor II Assay, P

Useful For

Diagnosing a congenital deficiency (rare) of coagulation factor II

 

Evaluating acquired deficiencies associated with liver disease or vitamin K deficiency, oral anticoagulant therapy, and antibody-induced deficiencies (eg, in association with lupus-like anticoagulant)

 

Determining warfarin treatment stabilization in patients with nonspecific inhibitors (ie, lupus anticoagulant)

 

Determining degree of anticoagulation with warfarin to correlate with level of protein S

 

Investigation of prolonged prothrombin time or activated partial thromboplastin time

Method Name

Prothrombin Clot-Based Assay

Performing Laboratory

Mayo Medical Laboratories in Rochester

Specimen Type

Plasma Na Cit


Specimen Required


See Coagulation Studies in Special Instructions.

 

Specimen Type: Platelet-poor plasma

Collection Container/Tube: Light-blue top (citrate)

Submission Container/Tube: Plastic vial

Specimen Volume: 1 mL

Collection Instructions:

1. Spin down, remove plasma, and spin plasma again.

2. Freeze specimen immediately at ≤-40° C, if possible.

Additional Information:

1. Double-centrifuged specimen is critical for accurate results as platelet contamination may cause spurious results.

2. Patient must not be receiving Coumadin or heparin therapy.

3. Each coagulation assay requested should have its own vial.

4. If priority specimen, mark request form, give reason, and request a call-back.

5. Coagulation testing is highly complex, often requiring the performance of multiple assays and correlation with clinical information. For that reason we suggest ordering Coagulation Consultations.


Specimen Minimum Volume

0.5 mL

Specimen Stability Information

Specimen Type Temperature Time
Plasma Na Cit Frozen 14 days

Reject Due To

Hemolysis

Mild OK; Gross reject

Lipemia

Mild OK; Gross reject

Icterus

Mild OK; Gross reject

Other

NA

Special Instructions

Reference Values

Adults: 75-145%

Normal, full-term newborn infants or healthy premature infants may have decreased levels (≥25%) which may remain below adult levels for ≥180 days postnatal.*

 *See Pediatric Hemostasis References in Coagulation Studies in Special Instructions.

Day(s) and Time(s) Performed

Monday through Friday

CPT Code Information

85210

LOINC Code Information

Test ID Test Order Name Order LOINC Value
F_2 Coag Factor II Assay, P 3289-6

 

Result ID Test Result Name Result LOINC Value
F_2 Coag Factor II Assay, P 3289-6

Test Classification

This test has been modified from the manufacturer's instructions. Its performance characteristics were determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.

Analytic Time

1 day