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Test Code FBILM Biliary Tract Malignancy-Cytology, FISH

Specimen Required


PreservCyt Vial (T536)

CytoLyt Solution (T564)

Specimen Type: Bile duct brushing, bile duct aspirate, hepatobiliary brushing, or hepatobiliary aspirate

Container/Tube: Separate ThinPrep vial containing 20 mL PreservCyt (T536) or CytoLyt solution (T564) for each specimen

Specimen Volume: Entire collection

Collection Instructions: Label with site specimen was collected from (eg, right hepatic duct or common bile duct).


If not ordering electronically, complete, print, and send 1 of the following forms with the specimen:

Pathology Test Request Form (T246) (

Oncology Test Request Form (T729) (

Useful For

Assessing bile duct brushing or hepatobiliary brushing specimens for malignancy

Testing Algorithm

When this test is ordered, FISH testing will be performed. When additional specimens are received, the laboratory will add BILMA to the first specimen, BILMB to the second specimen, BILMC to the third specimen, and so on.

Method Name

Cytology Light Microscopy and Fluorescence In Situ Hybridization (FISH)

Reporting Name

Biliary Tract Malignancy-Cyto/FISH

Specimen Type


Specimen Minimum Volume

20 mL

Specimen Stability Information

Specimen Type Temperature Time
Varies Refrigerated (preferred)

Reject Due To








Pancreatic mass, cyst, or fine-needle aspiration (FNA)

Reference Values

Negative for malignancy.

Day(s) and Time(s) Performed

Monday through Friday; 8 a.m.-5 p.m.

Analytic Time

5 days

Performing Laboratory

Mayo Medical Laboratories in Rochester

Test Classification

This test was developed using an analyte specific reagent. Its performance characteristics were determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.

CPT Code Information


88377-BILMA/BILMB/etc (if appropriate)

LOINC Code Information

Test ID Test Order Name Order LOINC Value
FBILM Biliary Tract Malignancy-Cyto/FISH In Process


Result ID Test Result Name Result LOINC Value
71291 Interpretation In Process
71292 Participated in the Interpretation No LOINC Needed
71293 Report electronically signed by In Process
71294 Addendum In Process
71295 Gross Description In Process
CY070 Collection Procedure In Process
CY042 Source 31208-2
CY043 Clinical History In Process
CY044 Fixative In Process
71570 Disclaimer 62364-5
71816 Case Number In Process

Reflex Tests

Test ID Reporting Name Available Separately Always Performed
BILMB Biliary Tract Malignancy, FISH No No
BILMC Biliary Tract Malignancy, FISH No No
BILMD Biliary Tract Malignancy, FISH No No
BILME Biliary Tract Malignancy, FISH No No
BILMF Biliary Tract Malignancy, FISH No No

Additional Tests

Test ID Reporting Name Available Separately Always Performed
BILMA Biliary Tract Malignancy, FISH No Yes