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Test Code GENTP Gentamicin Level Peak, LAB28

Performing Laboratory

St. Luke's Hospital Cedar Rapids

Specimen Requirements

 

Container/Tube:

Preferred:  Mint green-top (lithium heparin) tube

Acceptable:  Green-top tube, gold-top serum gel tube or plain, red-top tube

Specimen Volume: 0.1 mL serum or plasma

Stability:  Samples should be physically separated from cells as soon as possible with a maximum limit of 2 hours from the time of collection.  Separated specimens stored at 2 – 8°C and analyzed within 72 hours

Collection Instructions: Peak level should be drawn 1 hour post dose (intramuscular) or 30 to 60 minutes post dose (intravenous).  Specimens should not be drawn or stored in glass.

Note: Gentamicin time to steady state is after 2.5 to 75 hours of chronic dosing.

 

Reference Values

Therapeutic range: 5-10 mcg/mL

Critical value: >12 mcg/mL

Useful For

Gentamicin is an aminoglycoside antibiotic which exhibits high potency and a broad spectrum bacterial action against both gram-negative and gram-positive organisms.  It exhibits a narrow therapeutic index which makes its use hazardous, especially in patients with impaired renal function.

Day(s) Test Set Up

Monday through Sunday

Methodology

Turbidimetric Inhibition Immunoassay

Test Classification and CPT Coding

80170