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Test Code HIVDIM HIV-1 and HIV-2 Antibody Confirmation and Differentiation, Serum

Additional Codes








Useful For

Confirmation and differentiation of HIV-1 and HIV-2 antibodies in serum specimens that show reactive results with third- (HIV-1/-2 antibody only) and fourth- (HIV antigen and antibody) generation HIV serologic assays

Testing Algorithm

This HIV-1 and HIV-2 antibody confirmation and differentiation test begins with Geenius HIV-1/2 Supplemental Assay (Bio-Rad Laboratories).


For explanation of testing algorithm involving this assay, see HIV Testing Algorithm (Fourth Generation Screening Assay) including Follow-up of Reactive HIV Rapid Serologic Test Results in Special Instructions.

Reporting Name

HIV Ab Confirm / Differentiation, S

Specimen Type


Specimen Required

Collection Container/Tube:

Preferred: Serum gel

Acceptable: Red top

Submission Container/Tube: Plastic vial

Specimen Volume: 1 mL

Collection Instructions: Spin down and remove serum from clot within 24 hours.

Additional Information: If specimens are autopsy or cadaver blood sources, the proper FDA-licensed assay is HV1CD / HIV-1 and HIV-2 Antibodies for Cadaveric or Hemolyzed Specimens, Serum.

Specimen Stability Information

Specimen Type Temperature Time
Serum Frozen (preferred) 30 days
  Refrigerated  14 days
  Ambient  48 hours

Reject Due To


Mild OK; Gross reject


Mild OK; Gross reject


Mild OK; Gross reject



Reference Values



See HIV Serologic Interpretive Guide in Special Instructions for further interpretive information.

Day(s) and Time(s) Performed

Monday through Friday; Varies

Analytic Time

1 day

Performing Laboratory

Mayo Medical Laboratories in Rochester

Test Classification

This test has been cleared or approved by the U.S. Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.

CPT Code Information

86701-HIV-1 Antibody

86702-HIV-2 Antibody

LOINC Code Information

Test ID Test Order Name Order LOINC Value
HIVDI HIV Ab Confirm / Differentiation, S In Process


Result ID Test Result Name Result LOINC Value
36112 HIV-1 Ab Differentiation, S 68961-2
36113 HIV-2 Ab Differentiation, S 81641-3

Specimen Minimum Volume

0.1 mL

Method Name

Rapid Immunochromatographic Assay