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Test Code MISCLM Thyroglobulin, Tumor Marker Reflex to LC-MS/MS or Immunoassay

Additional Codes

 

MAYO Test ID

HTGR

EPIC Test ID

LAB2608

 

Useful For

Reporting of accurate thyroglobulin results, depending on the anti-thyroglobulin antibodies status of the patient

 

Accurate measurement of serum thyroglobulin in patients with known or suspected anti-thyroglobulin autoantibodies or possible heterophile antibodies

Testing Algorithm

This test begins with the analysis of thyroglobulin antibody by immunoassay. If the thyroglobulin antibody result is negative (<4.0 IU/mL), thyroglobulin testing will be performed by immunoassay. If the thyroglobulin antibody result is positive (≥4.0 IU/mL), thyroglobulin testing will be performed by mass spectrometry.

Reporting Name

Thyroglobulin Reflex to MS or IA

Specimen Type

Serum Red


Specimen Required


Container/Tube: Red top

Specimen Volume: 1 mL

Collection Instructions: Red-top tubes should be centrifuged and aliquoted within 2 hours of collection.

Additional Information: Twelve hours before this blood test, do not take multivitamins or dietary supplements containing biotin or vitamin B7 that are commonly found in hair, skin and nail supplements and multivitamins.


Specimen Minimum Volume

1.0 mL

Specimen Stability Information

Specimen Type Temperature Time
Serum Red Refrigerated (preferred) 7 days
  Frozen  30 days

Reject Due To

Hemolysis

Mild OK; Gross reject

Lipemia

Mild OK; Gross OK

Icterus

NA

Other

Plasma, serum gel tube, whole blood

Reference Values

Thyroglobulin Antibody: <4.0 IU/mL

Day(s) and Time(s) Performed

TGABR and HTGT: Monday through Friday 6 a.m.-12 a.m., Saturday 6 a.m.-6 p.m.

TGMS: Monday through Friday, 4 p.m.

Analytic Time

1 day if thyroglobulin antibody result is negative or 2 to 3 days if positive

Performing Laboratory

Mayo Medical Laboratories in Rochester

Test Classification

This test has been cleared or approved by the U.S. Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.

CPT Code Information

86800

LOINC Code Information

Test ID Test Order Name Order LOINC Value
HTGR Thyroglobulin Reflex to MS or IA 3013-0

 

Result ID Test Result Name Result LOINC Value
TGABR Thyroglobulin Antibody, S 56536-6

Reflex Tests

Test ID Reporting Name Available Separately Always Performed
HTGT Thyroglobulin, Tumor Marker, IA, S No No
TGMS Thyroglobulin, Mass Spec., S Yes No

Method Name

Immunoenzymatic Assay