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Test Code MISCLM C2 Complement, Functional, Serum

Additional Codes



Reporting Name

C2 Complement, Functional, S, NR

Useful For

Investigation of a patient with a low (absent) hemolytic complement (CH50)

Method Name

Automated Liposome Lysis Assay

Performing Laboratory

Mayo Medical Laboratories in Rochester

Specimen Type

Serum Red

Advisory Information

The total complement assay (COM / Complement, Total, Serum) should be used as a screen for suspected complement deficiencies before ordering individual complement component assays. A deficiency of an individual component of the complement cascade will result in an undetectable total complement level.

To evaluate for C2, C3, and C4 in one orderable, consider ordering C2 / C2 Complement, Functional, with Reflex, Serum.

Specimen Required

Patient Preparation: Fasting preferred but not required

Supplies: Aliquot Tube, 5 mL (T465)

Collection Container/Tube: Red top

Submission Container/Tube: Plastic, 5-mL tube (T465)

Specimen Volume: 1 mL

Collection Instructions:

1. Immediately after drawing the specimen, place the tube on wet ice.

2. Spin down and separate serum from clot.

3. Immediately freeze specimen.

Specimen Minimum Volume

0.5 mL

Specimen Stability Information

Specimen Type Temperature Time
Serum Red Frozen 21 days

Reject Due To


Mild OK; Gross OK


Mild OK; Gross reject


Mild OK; Gross OK


Serum gel tube

Reference Values

25-47 U/mL

Day(s) and Time(s) Performed

Monday through Saturday; 3 p.m.

CPT Code Information


LOINC Code Information

Test ID Test Order Name Order LOINC Value
C2FXN C2 Complement, Functional, S, NR In Process


Result ID Test Result Name Result LOINC Value
C2FX C2 Complement,Functional,S No LOINC Needed
INT53 Interpretation 69048-7

Analytic Time

Same day/1 day

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.