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Test Code MISCLM Apolipoprotein A1 and B, Plasma

Additional Codes

MAYO Test ID
APABR
EPIC Test ID
LAB2608

 

Useful For

Assessment of residual risk in patients at target non-HDL-C (or LDL-C)

 

Follow-up studies in individuals with non-HDL-C (or LDL-C) values inconsistent with risk factors or clinical presentation

 

Definitive studies of cardiac risk factors in individuals with significant family histories of coronary artery disease or other increased risk factors

Profile Information

Test ID Reporting Name Available Separately Always Performed
APLA1 Apolipoprotein A1, P Yes Yes
APLB Apolipoprotein B, P Yes Yes
RBAA Apolipoprotein B/A1 ratio No Yes

Method Name

Automated Turbidimetric Immunoassay

Reporting Name

Apolipoprotein A1 and B, P

Specimen Type

Plasma EDTA


Specimen Required


Collection Container/Tube: Lavender top (EDTA)

Submission Container/Tube: Plastic vial

Specimen Volume: 1 mL

Collection Instructions: Centrifuge and aliquot 1 mL of plasma. Send refrigerated.


Specimen Minimum Volume

0.5 mL

Specimen Stability Information

Specimen Type Temperature Time
Plasma EDTA Refrigerated (preferred) 8 days
  Frozen  60 days

Reject Due To

Hemolysis

Mild OK; Gross reject

Lipemia

Mild OK; Gross OK

Icterus

Mild OK; Gross reject

Other

NA

Reference Values

Males

Age

Apolipoprotein A (mg/dL)

Apolipoprotein B (mg/dL)

Apolipoprotein B/A1 ratio

<24 months

Not established

Not established

Not established

2-17 years

Low: <115

Borderline low: 115-120

Acceptable: >120

Acceptable: <90

Borderline high: 90-109

High: ≥110

<0.8

>18 years

≥120

Desirable: <90

Above Desirable: 90-99

Borderline high: 100-119

High: 120-139

Very high: ≥140

 

Lower Risk: <0.7

Average Risk: 0.7-0.9

Higher Risk: >0.9

Females

Age

Apolipoprotein A (mg/dL)

Apolipoprotein B (mg/dL)

Apolipoprotein B/A1 ratio

<24 months

Not established

Not established

Not established

2-17 years

Low: <115

Borderline low: 115-120

Acceptable: >120

Acceptable: <90

Borderline high: 90-109

High: ≥110

<0.8

>18 years

≥140

Desirable: <90

Above Desirable: 90-99

Borderline high: 100-119

High: 120-139

Very high: ≥140

 

Lower Risk: <0.6

Average Risk: 0.6-0.8

Higher Risk: >0.8

Day(s) and Time(s) Performed

Monday through Saturday; Continuously

Analytic Time

1 day

Performing Laboratory

Mayo Medical Laboratories in Rochester

Test Classification

This test has been cleared or approved by the U.S. Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.

CPT Code Information

82172 x 2

LOINC Code Information

Result ID Test Result Name Result LOINC Value
APLA1 Apolipoprotein A1, P 1869-7
APLB Apolipoprotein B, P 1884-6
RBAA Apolipoprotein B/A1 ratio 1874-7

Forms

If not ordering electronically, complete, print, and send a Cardiovascular Test Request Form (T724) with the specimen (http://www.mayomedicallaboratories.com/it-mmfiles/cardiovascular-request-form.pdf).