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Test Code MOGFS Myelin Oligodendrocyte Glycoprotein (MOG-IgG1) Fluorescence-Activated Cell Sorting (FACS) Assay, Serum


Specimen Required


Patient Preparation: For optimal antibody detection, we recommend drawing the specimen before initiation of immunosuppressant medication.

Container/Tube:

Preferred: Red top

Acceptable: Serum gel

Specimen Volume: 2 mL


Useful For

Diagnosis of inflammatory demyelinating diseases (IDD) with similar phenotype to neuromyelitis optica spectrum disorder (NMOSD), including optic neuritis (single or bilateral) and transverse myelitis

 

Diagnosis of autoimmune myelin oligodendrocyte glycoprotein (MOG)-opathy

 

Diagnosis of neuromyelitis optica (NMO)

 

Distinguishing NMOSD, acute disseminated encephalomyelitis (ADEM), optic neuritis, and transverse myelitis from multiple sclerosis early in the course of disease

 

Diagnosis of ADEM

 

Prediction of a relapsing disease course

Reflex Tests

Test ID Reporting Name Available Separately Always Performed
MOGTS MOG FACS Titer, S No No

Testing Algorithm

When the results of this assay require further evaluation, the reflex titer test will be performed at an additional charge.

Method Name

Flow Cytometry

Reporting Name

MOG FACS, S

Specimen Type

Serum

Specimen Minimum Volume

1 mL

Specimen Stability Information

Specimen Type Temperature Time
Serum Refrigerated (preferred) 28 days
  Frozen  28 days
  Ambient  72 hours

Reject Due To

Hemolysis

Mild OK; Gross Reject

Lipemia

Mild OK; Gross Reject

Icterus

Mild OK; Gross Reject

Other

NA

Reference Values

Negative

Day(s) and Time(s) Performed

Monday, Tuesday, Thursday; 6 p.m.

Analytic Time

5 days

Performing Laboratory

Mayo Medical Laboratories in Rochester

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.

CPT Code Information

86255

86256 (if appropriate)

LOINC Code Information

Test ID Test Order Name Order LOINC Value
MOGFS MOG FACS, S In Process

 

Result ID Test Result Name Result LOINC Value
65563 MOG FACS, S In Process