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Test Code MUSK Muscle-Specific Kinase (MuSK) Autoantibody, Serum

Additional Codes

 

MAYO Test ID

MUSK

EPIC Test ID

LAB2619

 

Useful For

Diagnosis of autoimmune muscle-specific kinase (MuSK) myasthenia gravis

 

Second-order test to aid in the diagnosis of autoimmune myasthenia gravis when first-line serologic tests are negative

 

Establishing a quantitative baseline value for MuSK antibodies that allows comparison with future levels if weakness is worsening

Testing Algorithm

See Myasthenia Gravis Evaluation with MuSK Reflex Algorithm in Special Instructions.

Reporting Name

MuSK Autoantibody, S

Specimen Type

Serum


Specimen Required


Container/Tube:

Preferred: Red top

Acceptable: Serum gel

Specimen Volume: 2 mL


Specimen Minimum Volume

0.5 mL

Specimen Stability Information

Specimen Type Temperature Time
Serum Refrigerated (preferred) 28 days
  Frozen  28 days
  Ambient  72 hours

Reject Due To

Hemolysis

Mild OK; Gross OK

Lipemia

Mild OK; Gross OK

Icterus

Mild OK; Gross OK

Other

NA

Reference Values

≤0.02 nmol/L

Day(s) and Time(s) Performed

Tuesday and Thursday; 6:00 a.m.

Analytic Time

3 days

Performing Laboratory

Mayo Medical Laboratories in Rochester

Test Classification

This test was developed using an analyte specific reagent. Its performance characteristics were determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.

CPT Code Information

83519

LOINC Code Information

Test ID Test Order Name Order LOINC Value
MUSK MuSK Autoantibody, S In Process

 

Result ID Test Result Name Result LOINC Value
64277 MuSK Autoantibody, S 51716-9

Method Name

Radioimmunoassay (RIA)

Forms

If not ordering electronically, complete, print, and send a Neurology Specialty Testing Client Test Request (T732) with the specimen (http://www.mayomedicallaboratories.com/it-mmfiles/neurology-request-form.pdf)