Sign in →

Test Code PGXFP Focused Pharmacogenomics Panel


Specimen Required


Submit only 1 of the following specimens:

 

Specimen Type: Whole blood

Container/Tube: Lavender top (EDTA)

Specimen Volume: 3 mL

Collection Instructions:

1. Invert several times to mix blood.

2. Send specimen in original tube.

Specimen Stability Information: Ambient (preferred)/Refrigerated

 

Specimen Type: Saliva

Patient Preparation: Patient should not eat, drink smoke, or chew gum 30 minutes prior to collection.

Supplies: DNA Saliva Collection Kit (T786)

Container/Tube: Saliva Swab Collection Kit (T786: fees apply)

Specimen Volume: 1 swab

Collection Instructions: Collect and send specimen per kit instructions.

Specimen Stability Information: Ambient

Additional Information: Due to lower concentration of DNA yielded from saliva, testing cannot proceed to reflex testing for 2D6 sequencing and will stop after initial testing is complete.

 

Specimen Type: DNA

Container/Tube: 2 mL screw top tube

Specimen Volume: 100 mcL (microliters)

Collection Instructions:

1. The preferred volume is 100 mcL at a concentration of 50 ng/mcL.

2. Include concentration and volume on tube.

Specimen Stability Information: Frozen (preferred)/Ambient/Refrigerated


Forms

1. New York Clients-Informed consent is required. Please document on the request form or electronic order that a copy is on file. An Informed Consent for Genetic Testing (T576) is available in Special Instructions.

2. If not ordering electronically, complete, print, and send a Neurology Specialty Testing Client Test Request (T732) with the specimen (http://www.mayomedicallaboratories.com/it-mmfiles/neurology-request-form.pdf)

Useful For

Preemptive or reactive genotyping of patients for pharmacogenomic purposes

 

Providing an assessment for genes with strong drug-gene associations

Testing Algorithm

If a specimen requires follow-up for CYP2D6, then reflex testing will be performed as appropriate at an additional charge.

 

See CYP2D6 Comprehensive Cascade Testing Algorithm in Special Instructions.

Method Name

Real Time Polymerase Chain Reaction (RT-PCR) with Allelic Discrimination Analysis with Polymerase Chain Reaction (PCR) Followed by DNA Sequence Analysis when appropriate

Reporting Name

Focused Pharmacogenomics Panel

Specimen Type

Varies

Specimen Minimum Volume

Blood: 1 mL
Saliva: 1 swab

Specimen Stability Information

Specimen Type Temperature Time
Varies Varies

Reject Due To

Hemolysis

NA

Lipemia

NA

Icterus

NA

Other

NA

Reference Values

An interpretive report will be provided.

Day(s) and Time(s) Performed

Monday through Friday; 8 a.m.

Analytic Time

3 days (not reported Saturday or Sunday)

Performing Laboratory

Mayo Medical Laboratories in Rochester

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.

CPT Code Information

81479-CYP1A2 Unlisted molecular pathology procedure

81225-CYP2C19

81226-CYP2D6

81227-CYP2C9

81355-VKORC1

81479-SLCO1B1 Unlisted molecular pathology procedure

81401-CYP3A4

81401-CYP3A5

81479-CYP4F2 Unlisted molecular pathology procedure

81479-CYP2C locus Unlisted molecular pathology procedure

2D6S1

81479-Unlisted molecular pathology procedure (if appropriate)

2D6S2

81479-Unlisted molecular pathology procedure (if appropriate)

2D6S3

81479-Unlisted molecular pathology procedure (if appropriate)

2D6S4

81479-Unlisted molecular pathology procedure (if appropriate)

2D6S5

81479-Unlisted molecular pathology procedure (if appropriate)

2D6S6

81479-Unlisted molecular pathology procedure (if appropriate)

LOINC Code Information

Test ID Test Order Name Order LOINC Value
PGXFP Focused Pharmacogenomics Panel In Process

 

Result ID Test Result Name Result LOINC Value
BA0902 Medications 52418-1
BA0903 Amitriptyline In Process
BA0904 Aripiprazole In Process
BA0905 Atomoxetine In Process
BA0906 Atorvastatin In Process
BA0914 Brexpiprazole In Process
BA0907 Carvedilol In Process
BA0915 Carisoprodol In Process
BA0908 Celecoxib In Process
BA0909 Citalopram In Process
BA0152 Clobazam In Process
BA0910 Clomipramine In Process
BA0911 Clopidogrel In Process
BA0912 Codeine In Process
BA0913 Desipramine In Process
BA0263 Dexlansoprazole In Process
BA0235 Dextromethorphan In Process
BA0916 Diclofenac In Process
BA0917 Doxepin In Process
BA0233 Eliglustat In Process
BA0918 Escitalopram In Process
BA0919 Esomeprazole In Process
BA0244 Flecainide In Process
BA0920 Fluoxetine In Process
BA0921 Fluvoxamine In Process
BA0922 Fosphenytoin In Process
BA0245 Haloperidol In Process
BA1630 Iloperidone In Process
BA0923 Imipramine In Process
BA0924 Lansoprazole In Process
BA0925 Metoprolol In Process
BA0926 Nortriptyline In Process
BA0927 Omeprazole In Process
BA0928 Ondansetron In Process
BA0929 Oxycodone In Process
BA0930 Pantoprazole In Process
BA0931 Paroxetine In Process
BA1631 Perphenazine In Process
BA0932 Phenytoin In Process
BA1632 Pimozide In Process
BA0933 Pravastatin In Process
BA1633 Propafenone In Process
BA1634 Risperidone In Process
BA0934 Rosuvastatin In Process
BA0935 Sertraline In Process
BA0936 Simvastatin In Process
BA0937 Sirolimus In Process
BA0938 Tacrolimus In Process
BA0939 Tamoxifen In Process
BA0940 Tamsulosin In Process
BA1635 Tetrabenazine In Process
BA1636 Thioridazine In Process
BA0941 Tramadol In Process
BA0942 Trimipramine In Process
BA0943 Tropisetron In Process
BA0944 Venlafaxine In Process
BA0945 Voriconazole In Process
BA0946 Warfarin In Process
BA0947 Other Medications In Process
BA0261 CYP1A2 Genotype In Process
BA0262 CYP1A2 Phenotype In Process
BA0258 CYP2C19 Genotype In Process
BA0259 CYP2C19 Phenotype 79714-2
BA0264 CYP2C9 Genotype In Process
BA0265 CYP2C9 Phenotype 79716-7
BA0255 CYP2D6 Genotype In Process
BA0256 CYP2D6 Phenotype 79715-9
BA0252 CYP3A4 Genotype In Process
BA0253 CYP3A4 Phenotype In Process
BA0249 CYP3A5 Genotype In Process
BA0250 CYP3A5 Phenotype 79717-5
BA0246 SLCO1B1 Genotype In Process
BA0247 SLCO1B1 Phenotype 79722-5
BA0228 WARF CYP2C9 Genotype In Process
BA0229 WARF VKORC1 Genotype In Process
BA0150 Additional VKORC1 Variants In Process
BA0230 CYP4F2 *3 Genotype In Process
BA0231 rs12777823 Genotype In Process
BA0151 Interpretation In Process
BA0267 Additional Information In Process
BA0268 Method 49549-9
BA0269 Disclaimer 62364-5
BA0270 Reviewed by In Process