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Test Code PHEP Previous Hepatitis (Unknown Type)

Shipping Instructions


Necessary Information

Date of draw is required.

Specimen Required

Both 0.5 mL of refrigerated serum and 2.5 mL of frozen serum are required for this test.


Patient Preparation: For 12 hours before this test do not take multivitamins or dietary supplements containing biotin (vitamin B7), which is commonly found in hair, skin, and nail supplements and multivitamins.

Collection Container/Tube: Serum gel

Submission Container/Tube: Plastic vial

Specimen Volume: 3 mL

Collection Instructions: Spin down within 6 hours of draw.

Useful For

Determining if an individual has been infected following exposure to an unknown type of hepatitis


Obtaining baseline serologic markers of an individual exposed to a source with an unknown type of hepatitis


Determining immunity to hepatitis A and B viral infections

Profile Information

Test ID Reporting Name Available Separately Always Performed
HAIGG Hepatitis A IgG Ab, S Yes Yes
HBAG HBs Antigen, S Yes Yes
HBAB HBs Antibody, S Yes Yes
HBC HBc Total Ab, S Yes Yes
HCVDX HCV Ab w/Reflex to HCV PCR, S Yes Yes

Testing Algorithm

If hepatitis C virus (HCV) antibody is reactive, then HCV RNA detection and quantification by real-time reverse transcription-PCR will be performed at an additional charge.


If hepatitis B surface antigen (HBsAg) is reactive, then HBsAg confirmation will be performed at an additional charge.


The following algorithms are available in Special Instructions:

-HBV Infection-Diagnostic Approach and Management Algorithm

-Hepatitis C: Testing Algorithm for Screening and Diagnosis

Method Name

Chemiluminescence Immunoassay (CIA)

Reporting Name

Previous Hepatitis Profile

Specimen Type

Serum SST

Specimen Minimum Volume

2.5 mL

Specimen Stability Information

Specimen Type Temperature Time
Serum Refrigerated 5 days
Serum SST Frozen (preferred) 30 days
  Refrigerated  5 days

Reject Due To


Mild OK; Gross reject


Mild OK; Gross reject


Mild OK; Gross reject


Plasma, red-top serum, heat-inactivated specimen

Reference Values

Hepatitis B Surface Antigen



Hepatitis B Surface Antigen Confirmation



Hepatitis B Surface Antibody, Qualitative/Quantitative


Hepatitis B Surface Antibody

Unvaccinated: negative

Vaccinated: positive


Hepatitis B Surface Antibody, Quantitative

Unvaccinated: <5.0 mIU/mL

Vaccinated: ≥12.0 mIU/mL


Hepatitis B Core Total Antibodies



Hepatitis A IgG Antibody

Unvaccinated: Negative

Vaccinated: Positive


Hepatitis C Antibody



HCV RNA Detection and Quantification by Real-Time RT-PCR



Interpretation depends on clinical setting. See Viral Hepatitis Serologic Profiles in Special Instructions.

Day(s) and Time(s) Performed

Monday through Saturday; Varies

Analytic Time

1 day

Performing Laboratory

Mayo Medical Laboratories in Rochester

Test Classification

This test has been cleared or approved by the U.S. Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.

CPT Code Information

86704-Hepatitis B core total antibodies

86706-Hepatitis B surface antibody, qualitative/quantitative

86708-Hepatitis A antibody, total

86803-Hepatitis C antibody

87340-Hepatitis B surface antigen

87341-Hepatitis B surface antigen confirmation (if appropriate)

87522-Hepatitis C, quantification (if appropriate)

LOINC Code Information

Test ID Test Order Name Order LOINC Value
PHEP Previous Hepatitis Profile In Process


Result ID Test Result Name Result LOINC Value
HCVA4 HCV Ab, S 13955-0
HBC HBc Total Ab, S 13952-7
HB_AB HBs Antibody, S 10900-9
H_BAG HBs Antigen, S 5196-1
HAIGG Hepatitis A IgG Ab, S 40724-7
HBSQN HBs Antibody, Quantitative, S 5193-8

Reflex Tests

Test ID Reporting Name Available Separately Always Performed
HBGNT HBs Antigen Confirmation, S No No
HCVQN HCV RNA Detect/Quant, S Yes No