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Test Code PPMM Prometheus Thiopurine Metabolites

Additional Codes

 

 

MAYO Test ID

FPMET

EPIC Test ID

LAB2682

 

Reporting Name

Prometheus Thiopurine Metabolites

Performing Laboratory

Prometheus Laboratories, Inc. Therapeutics and Diagnostics

Specimen Type

Whole Blood EDTA


Specimen Required


Specimen Type: Whole Blood

Container/Tube: Lavender top (EDTA)

Specimen volume: 5 mL

Collection Instructions:  Send 5 mL whole blood in original tube refrigerated


Specimen Minimum Volume

Pediatric Minimum Volume: 3 mL

Specimen Stability Information

Specimen Type Temperature Time
Whole Blood EDTA Refrigerated (preferred) 8 days
  Ambient  72 hours

Reference Values

Units of Measure:  pmol/8 x 10(8) RBC

 

Metabolite                                                   Reference Range

6-TGN                                                                 230-400

6-MMPN                                                              <5700

 

Proprietary and patented technology by Prometheus Laboratories, Inc.  The therapeutic range and toxic thresholds were established in an IBD patient population receiving azathioprine or 6-mercaptopurine.  Metabolite testing should not replace laboratory monitoring for toxicity.

 

CPT Code Information

82542

LOINC Code Information

Test ID Test Order Name Order LOINC Value
FPMET Prometheus Thiopurine Metabolites In Process

 

Result ID Test Result Name Result LOINC Value
Z1501 6-TGN Metabolite Result 32660-3
Z1502 6-TGN Metabolite Result Assessment In Process
Z1503 6-MMPN Metabolite Result 32654-6
Z1504 6-MMPN Metabolite Result Assessment In Process

Analytic Time

3 days

Reject Due To

Hemolysis

Gross reject; Mild OK

Thawing

NA

Lipemia

NA

Icterus

NA

Other

Reject if specimen is other than EDTA whole blood

Method Name

High Pressure Liquid Chromatography (HPLC)

Forms

If not ordering electronically, complete, print, and send a Gastroenterology and Hepatology Test Request Form (T728) with the specimen (http://www.mayomedicallaboratories.com/it-mmfiles/gastroenterology-and-hepatology-test-request.pdf)