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Test Code PRIMM Primidone and Phenobarbital, Serum

Additional Codes

 

MAYO Test ID

PRMB

EPIC Test ID

LAB485

 

Useful For

Assessing compliance

 

Monitoring for appropriate therapeutic levels of primidone and phenobarbital

 

Assessing toxicity

Profile Information

Test ID Reporting Name Available Separately Always Performed
PRIMD Primidone, S No Yes
PBR Phenobarbital, S Yes Yes

Testing Algorithm

Includes phenobarbital determination.

Method Name

PRIMD: Immunoassay

PBR: Kinetic Interaction of Microparticles in a Solution (KIMS)

Reporting Name

Primidone and Phenobarbital, S

Specimen Type

Serum


Specimen Required


Container/Tube:

Preferred: Serum gel

Acceptable: Red top

Specimen Volume: 0.5 mL

Collection Instructions:

1. Serum gel tubes should be centrifuged within 2 hours of collection.

2. Red-top tubes should be centrifuged and aliquoted within 2 hours of collection.


Specimen Minimum Volume

0.25 mL

Specimen Stability Information

Specimen Type Temperature Time
Serum Refrigerated (preferred) 7 days
  Frozen  28 days
  Ambient  72 hours

Reject Due To

Hemolysis

Mild OK; Gross reject

Lipemia

NA

Icterus

NA

Other

NA

Reference Values

Primidone

Therapeutic: 5.0-12.0 mcg/mL

Critical value: ≥15.0 mcg/mL

 

Phenobarbital

Therapeutic: 10.0-40.0 mcg/mL

Critical value: ≥60.0 mcg/mL

Day(s) and Time(s) Performed

Monday through Sunday; Continuously

Analytic Time

Same day/1 day

Performing Laboratory

Mayo Medical Laboratories in Rochester

Test Classification

This test has been cleared or approved by the U.S. Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.

CPT Code Information

PRIMD-80188

PBR-80184

LOINC Code Information

Result ID Test Result Name Result LOINC Value
PBR Phenobarbital, S 3948-7
PRIMD Primidone, S 3978-4