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Test Code PSATF Prostate-Specific Antigen (PSA), Total and Free, Serum

Additional Codes

 

 

MAYO Test ID

PSAFT

EPIC Test ID

LAB171

 

 

Reporting Name

PSA Total and Free, S

Useful For

The percentage of measured prostate-specific antigen (PSA) existing in the free form (free:total PSA ratio) is useful in assessing the risk of prostate cancer in patients with borderline or moderately increased total PSA (4.0-10.0 ng/mL) and has been used to help select men who should have follow-up prostate biopsy

Method Name

Electrochemiluminescent Immunoassay (ECLIA)

Performing Laboratory

Mayo Medical Laboratories in Rochester

Specimen Type

Serum


Necessary Information


Include patient's age.



Specimen Required


Patient Preparation: For 12 hours before this blood test do not take multivitamins or dietary supplements containing biotin or vitamin B7, which are commonly found in hair, skin and nail supplements and multivitamins.

Collection Container/Tube:

Preferred: Serum gel

Acceptable: Red top

Submission Container/Tube: Plastic vial

Specimen Volume: 1 mL

Collection Instructions: Spin down within 3 hours of draw and separate serum from cells.

Additional Information: Free prostate-specific antigen (PSA) can only be added on within 12 hours of performing total PSA. Specimen must have been shipped frozen.


Specimen Minimum Volume

0.5 mL

Specimen Stability Information

Specimen Type Temperature Time
Serum Frozen 90 days

Reject Due To

Hemolysis

Mild OK; Gross reject

Lipemia

Mild OK; Gross OK

Icterus

NA

Other

NA

Reference Values

TOTAL PSA

Males:

Age (Years)

PSA Upper Limit (ng/mL)

<40

≤2.0

40-49

≤2.5

50-59

≤3.5

60-69

≤4.5

70-79

≤6.5

≥80

≤7.2

 

Females: not applicable

 

FREE PSA

Males: When total PSA is in the range of 4.0-10.0 ng/mL, a free:total PSA ratio ≤0.10 indicates 49% to 65% risk of prostate cancer depending on age; a free:total PSA ratio >0.25 indicates a 9% to 16% risk of prostate cancer, depending on age.

Females: not applicable

Day(s) and Time(s) Performed

Monday through Friday; 5 a.m.-12 a.m., Saturday; 6 a.m.-6 p.m.

CPT Code Information

84153-Total

84154-Free

LOINC Code Information

Test ID Test Order Name Order LOINC Value
PSAFT PSA Total and Free, S 53764-7

 

Result ID Test Result Name Result LOINC Value
TPSA Total PSA 2857-1
FPSA Free PSA 83113-1
PSA_R Free PSA/PSA Ratio 12841-3

Analytic Time

1 day

Test Classification

This test has been cleared or approved by the U.S. Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.

Forms

If not ordering electronically, complete, print, and send 1 of the following forms with the specimen:

General Request Form (T239) (http://www.mayomedicallaboratories.com/it-mmfiles/general-request-form.pdf)

Oncology Test Request Form (T729) (http://www.mayomedicallaboratories.com/it-mmfiles/oncology-request-form.pdf)