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Test Code PTSAFM Protein S Antigen, Plasma

Additional Codes

 

MAYO Test ID

PSTF

EPIC Test ID

LAB492

 

Reporting Name

Protein S Ag, P

Useful For

Investigation of patients with a history of thrombosis

Profile Information

Test ID Reporting Name Available Separately Always Performed
PSF Protein S Ag, Free, P No Yes

Reflex Tests

Test ID Reporting Name Available Separately Always Performed
PST Protein S Ag, Total, P No No

Testing Algorithm

If this test is abnormal, then total plasma protein S antigen will be performed at an additional charge.

Method Name

PSF: Automated Latex Immunoassay (LIA)

PST: Latex Immunoassay (LIA)

Performing Laboratory

Mayo Medical Laboratories in Rochester

Specimen Type

Plasma Na Cit


Specimen Required


See Coagulation Studies in Special Instructions.

 

Specimen Type: Platelet-poor plasma

Collection Container/Tube: Light-blue top (citrate)

Submission Container/Tube: Plastic vials

Specimen Volume: 1 mL in 2 plastic vials each containing 0.5 mL

Collection Instructions:

1. Spin down, remove plasma, and spin plasma again.

2. Freeze specimens immediately at ≤-40 degrees C, if possible.

3. Send specimens in the same shipping container.

Additional Information:

1. Double-centrifuged specimen is critical for accurate results as platelet contamination may cause spurious results.

2. If the patient is being treated with Coumadin, this should be noted. Coumadin will lower protein S.

3. Patient must not be receiving heparin or Coumadin.


Specimen Minimum Volume

0.5 mL

Specimen Stability Information

Specimen Type Temperature Time
Plasma Na Cit Frozen 14 days

Reject Due To

Hemolysis

Mild OK; Gross reject

Lipemia

Mild OK; Gross reject

Icterus

NA

Other

NA

Special Instructions

Reference Values

TOTAL

Males: 80-160%

Females

<50 years: 70-160%

≥50 years: 80-160%

 

FREE

Males: 65-160%

Females

<50 years: 50-160%

≥50 years: 65-160%

Normal, full-term newborn infants or healthy premature infants may have decreased levels of total protein S (15-50%); but because of low levels of C4bBP, free protein S may be normal or near the normal adult level (≥50%). Total protein S reaches adult levels by 90 to 180 days postnatal.*

Day(s) and Time(s) Performed

Monday through Friday

CPT Code Information

85306-Free

85305-Total (if appropriate)

LOINC Code Information

Test ID Test Order Name Order LOINC Value
PSTF Protein S Ag, P 27821-8

 

Result ID Test Result Name Result LOINC Value
PSF Protein S Ag, Free, P 27821-8

Analytic Time

1 day

Test Classification

See Individual Test IDs