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Test Code RUBIMM Rubella Anitibody IgG, LAB496

Performing Laboratory

St. Luke's Hospital Cedar Rapids

Specimen Requirements

Container/Tube:

Preferred: Gold-top serum gel tube

Acceptable: Plain, red-top tube

Specimen Volume: 170 uL of serum

Stability: Store specimens at 2° – 8°C up to 7 days. Specimens may be stored on the clot for up to 3 days at 2° – 8°C.  Freeze samples, devoid of red blood cells, at or below -20°C for longer storage.  Specimens may undergo five freeze-thaw cycles.

Note: Human anti-mouse antibodies or other heterophile antibodies may be present in patient specimens. This assay has been specially formulated to minimize the effects of these antibodies, however results from patients known to have these antibodies should be carefully evaluated.

Reference Values

Value                           Status

<0.9 index                 Nonimmune

0.9-0.99 index           Equivocal

≥1.0 index                  Immune

Useful For

The detection of specific rubella antibodies is of great interest due to the teratogenic risk related to a rubella primary infection at the beginning of the pregnancy.

Infections in utero, particularly during the first four months of pregnancy, can lead to congenital defects such as deafness, cardiac problems, cataracts or glaucoma, and sometimes fetal death.

The infection is usually benign or even unapparent in children or adults.

Day(s) Test Set Up

Monday through Friday

Methodology

Indirect chemiluminescence immunoassay (CLIA)

Test Classification and CPT Coding

86762