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Test Code THYREM Thyrotropin Receptor Antibody, Serum

Additional Codes

 

MAYO Test ID

THYRO

EPIC Test ID

LAB3979

 

Reporting Name

Thyrotropin Receptor Ab, S

Useful For

Recommended first-line test for detection of thyrotropin receptor (TSHR) antibodies, and used in the following situations:

-Differential diagnosis of etiology of thyrotoxicosis in patients with ambiguous clinical findings and/or contraindicated (eg, pregnant or breast-feeding) or nondiagnostic thyroid radioisotope scans

-Diagnosis of clinically suspected Graves disease (eg, extrathyroidal manifestation of Graves disease include endocrine exophthalmos, pretibial myxedema, thyroid acropachy) in patients with normal thyroid function tests

-Determining the risk of neonatal thyrotoxicosis in a fetus of a pregnant female with active or past active Graves disease

-Differential diagnosis of gestational thyrotoxicosis versus first trimester manifestation or recurrence of Graves disease

-Assessing the risk of Graves disease relapse after antithyroid drug treatment

Method Name

Electrochemiluminescence Immunoassay

Performing Laboratory

Mayo Medical Laboratories in Rochester

Specimen Type

Serum


Specimen Required


Patient Preparation; For 12 hours before this test do not take multivitamins or dietary supplements containing biotin (vitamin B7), which is commonly found in hair, skin, and nail supplements and multivitamins.

Container/Tube:

Preferred: Red top

Acceptable: Serum gel

Specimen Volume: 1 mL


Specimen Minimum Volume

0.5 mL

Specimen Stability Information

Specimen Type Temperature Time
Serum Refrigerated (preferred) 7 days
  Frozen  30 days

Reject Due To

Hemolysis

Mild OK; Gross reject

Lipemia

Mild OK; Gross OK

Icterus

NA

Other

NA

Reference Values

≤1.75 IU/L

Day(s) and Time(s) Performed

Monday through Friday 5 a.m. - 12 a.m., Saturday 6 a.m. - 6 p.m.

CPT Code Information

83520

LOINC Code Information

Test ID Test Order Name Order LOINC Value
THYRO Thyrotropin Receptor Ab, S 5385-0

 

Result ID Test Result Name Result LOINC Value
THYRO Thyrotropin Receptor Ab, S 5385-0

Analytic Time

1 day / same day

Test Classification

This test has been cleared or approved by the U.S. Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.

Forms

If not ordering electronically, complete, print, and send a General Request Form (T239) with the specimen (http://www.mayomedicallaboratories.com/it-mmfiles/general-request-form.pdf)