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Test Code TTGIGM Tissue Transglutaminase (tTG) Antibodies, IgA and IgG Profile, Serum

Additional Codes

 

MAYO Test ID

TSTGP

EPIC Test ID

LAB2968

 

Reporting Name

Tissue Transglutaminase Ab, IgA/IgG

Useful For

Evaluating patients suspected of having celiac disease, including patients with compatible clinical symptoms, patients with atypical symptoms, and individuals at increased risk (family history, previous diagnosis with associated disease, positivity for HLA DQ2 and/or DQ8)

 

Monitoring adherence to gluten-free diet in patients with dermatitis herpetiformis and celiac disease

Profile Information

Test ID Reporting Name Available Separately Always Performed
TTGA Tissue Transglutaminase Ab, IgA, S Yes Yes
TTGG Tissue Transglutaminase Ab, IgG, S Yes Yes

Testing Algorithm

The following algorithms are available in Special Instructions:

-Celiac Disease Comprehensive Cascade

-Celiac Disease Diagnostic Testing Algorithm

-Celiac Disease Gluten-Free Cascade        

-Celiac Disease Routine Treatment Monitoring Algorithm

-Celiac Disease Serology Cascade

Method Name

Enzyme-Linked Immunosorbent Assay (ELISA)

Performing Laboratory

Mayo Medical Laboratories in Rochester

Specimen Type

Serum


Specimen Required


Container/Tube: 

Preferred: Serum gel

Acceptable: Red top

Specimen Volume: 0.50 mL


Specimen Minimum Volume

0.4 mL

Specimen Stability Information

Specimen Type Temperature Time
Serum Refrigerated (preferred) 7 days
  Frozen  14 days

Reject Due To

Hemolysis

Mild OK; Gross reject

Lipemia

Mild OK; Gross reject

Icterus

Mild OK; Gross OK

Other

NA

Reference Values

tTG ANTIBODY, IgA

<4.0 U/mL (negative)

4.0-10.0 U/mL (weak positive)

>10.0 U/mL (positive)

Reference values apply to all ages.

 

tTG ANTIBODY, IgG

<6.0 U/mL (negative)

6.0-9.0 U/mL (weak positive)

>9.0 U/mL (positive)

Reference values apply to all ages.

Day(s) and Time(s) Performed

Monday through Saturday; 4 p.m.

CPT Code Information

83516 x 2

LOINC Code Information

Test ID Test Order Name Order LOINC Value
TSTGP Tissue Transglutaminase Ab, IgA/IgG In Process

 

Result ID Test Result Name Result LOINC Value
TTGA Tissue Transglutaminase Ab, IgA, S 46128-5
TTGG Tissue Transglutaminase Ab, IgG, S 56537-4

Analytic Time

Same day/1 day

Test Classification

This test has been cleared or approved by the U.S. Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.

Forms

If not ordering electronically, complete, print, and send 1 of the following forms with the specimen:

General Request Form (T239) (http://www.mayomedicallaboratories.com/it-mmfiles/general-request-form.pdf)

Gastroenterology and Hepatology Test Request Form (T728) (http://www.mayomedicallaboratories.com/it-mmfiles/gastroenterology-and-hepatology-test-request.pdf)