Sign in →

Test Code UCORTM Cortisol, Free, 24 Hour, Urine

Additional Codes

 

MAYO Test ID

CORTU

EPIC Test ID

LAB382

 

Reporting Name

Cortisol, Free, U

Useful For

Preferred screening test for Cushing syndrome

 

Diagnosis of pseudo-hyperaldosteronism due to excessive licorice consumption

 

This test has limited usefulness in the evaluation of adrenal insufficiency

Method Name

Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)

Performing Laboratory

Mayo Medical Laboratories in Rochester

Specimen Type

Urine


Necessary Information


24-Hour volume is required.



Specimen Required


Supplies: Urine Tubes, 10-mL (T068)

Submission Container/Tube: Plastic, urine tube (T068)

Specimen Volume: 5 mL

Collection Instructions:

1. Collect urine for 24 hours.

2. Add 10 g of boric acid as preservative at start of collection.

Additional Information: See Urine Preservatives-Collection and Transportation for 24-Hour Urine Specimens in Special Instructions for multiple collections.


Specimen Minimum Volume

3 mL

Specimen Stability Information

Specimen Type Temperature Time
Urine Refrigerated (preferred) 14 days
  Frozen  28 days
  Ambient  7 days

Reject Due To

Hemolysis

NA

Lipemia

NA

Icterus

NA

Other

NA

Reference Values

0-2 years: not established

3-8 years: 1.4-20 mcg/24 hours

9-12 years: 2.6-37 mcg/24 hours

13-17 years: 4.0-56 mcg/24 hours

≥18 years: 3.5-45 mcg/24 hours

 

Use the factor below to convert from mcg/24 hours to nmol/24 hours:

 

Conversion factor

Cortisol: mcg/24 hours x 2.76=nmol/24 hours (molecular weight=362.5)

Day(s) and Time(s) Performed

Monday through Friday; 4 p.m.

CPT Code Information

82530

LOINC Code Information

Test ID Test Order Name Order LOINC Value
CORTU Cortisol, Free, U In Process

 

Result ID Test Result Name Result LOINC Value
8546 Cortisol, U 14158-0
TM93 Collection Duration 13362-9
VL47 Urine Volume 3167-4

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.

Analytic Time

2 days (not reported on Sundays)

Urine Preservative Collection Options

Ambient

No

Refrigerated

Yes

Frozen

Yes

6N HCl

No

50% Acetic Acid

Yes

Na2CO3

No

Toluene

Yes

6N HNO3

No

Boric Acid

Preferred

Thymol

No