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Test Code UHSID Hemosiderin, Random, Urine, LAB399


Prussian Blue Reaction

Performing Laboratory

St. Luke's Hospital Cedar Rapids

Specimen Requirements

15 mL from a first-morning, random urine collection. Forward promptly.

Reference Values


Day(s) Test Set Up

Monday through Friday (days only)

Test Classification and CPT Coding


Useful For

Renal epithelial cells containing granules of hemosiderin occasionally may be seen in the urinary sediment. Hemosiderin is a form of iron, formed by renal tubular epithelial cells from hemoglobin present in the renal tubules.  The presence of hemosiderin in the urine sediment 2 to 3 days after an acute hemolytic episode indicates severe intravascular hemolysis.  It is commonly seen in paroxysmal nocturnal hemoglobinuria and may be seen as the result of hemochromatosis.