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Test Code HCVDX Hepatitis C Antibody with Reflex to HCV RNA by PCR, Serum

Advisory Information

This test is not intended for testing asymptomatic individuals (ie, screening purposes). For testing such patients with or without risk factors for hepatitis C virus (HCV) infection, order HCSRN / Hepatitis C Antibody Screen with Reflex to HCV RNA by PCR, Serum.

Shipping Instructions

If shipment will be delayed for >24 hours, freeze serum at -70° C until shipment on dry ice.

Specimen Required

Collection Container/Tube: Serum gel

Submission Container/Tube: Plastic vial

Specimen Volume: 2 mL

Collection Instructions:

1. Centrifuge blood collection tube per collection tube manufacturer's instructions.

2. Pour off serum into aliquot tube.

Useful For

Diagnosis of recent or chronic hepatitis C virus infection in symptomatic patients

Testing Algorithm

If hepatitis C virus (HCV) antibody screen is reactive, then HCV RNA by RT-PCR will be performed at an additional charge.


See Hepatitis C: Testing Algorithm for Screening and Diagnosis in Special Instructions.

Method Name

Chemiluminescence Immunoassay

Reporting Name

HCV Ab w/Reflex to HCV PCR, S

Specimen Type

Serum SST

Specimen Minimum Volume

1 mL

Specimen Stability Information

Specimen Type Temperature Time
Serum SST Frozen (preferred) 30 days
  Refrigerated  5 days

Reject Due To


Mild OK; Gross reject


Mild OK; Gross reject


Mild OK; Gross reject


Heparinized specimen or red-top tube

Reference Values


See Viral Hepatitis Serologic Profiles in Special Instructions.

Day(s) and Time(s) Performed

Monday through Saturday; Varies

Analytic Time

1 day

Performing Laboratory

Mayo Medical Laboratories in Rochester

Test Classification

This test has been cleared or approved by the U.S. Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.

CPT Code Information


87522-(if appropriate)

LOINC Code Information

Test ID Test Order Name Order LOINC Value
HCVDX HCV Ab w/Reflex to HCV PCR, S 13955-0


Result ID Test Result Name Result LOINC Value
HCVA4 HCV Ab, S 13955-0

Reflex Tests

Test ID Reporting Name Available Separately Always Performed
HCVQN HCV RNA Detect/Quant, S Yes No