Sign in →

Test Code MISCLM Pyruvic Acid, Blood

Additional Codes







Reporting Name

Pyruvic Acid, B

Useful For

Screening for possible disorders of mitochondrial metabolism, when used in conjunction with blood lactate collected at the same time to determine the lactate-to-pyruvate ratio

Method Name

Spectrophotometry (SP)

Performing Laboratory

Mayo Medical Laboratories in Rochester

Specimen Type

Whole blood

Additional Testing Requirements

This test does not calculate the lactate:pyruvate ratio. To obtain this information, both LAA / Lactate, Plasma and PYR / Pyruvic Acid, Blood must be ordered. The ratio can be calculated from the results of those tests.

Specimen Required

Call Mayo Medical Laboratories at 800-533-1710 or 507-266-5700 to order special collection tube.


Patient Preparation: Fasting (at least 4 hours)

Supplies: Perchloric Acid–Pyruvate Tube (T012)

Container/Tube: Special collection tube containing 2.5 mL of 6% perchloric acid (T012)

Specimen Volume: Exactly 1 mL

Collection Instructions:

1. Special collection tube must be prechilled prior to draw.

2. Draw enough blood directly into syringe to add exactly 1 mL of blood to the prechilled special collection tube.

3. Once drawn, immediately transfer blood to the prechilled, special collection tube and shake vigorously to mix.

Additional Information:

1. Check expiration date before using. Supplied collection tube expires 12 months after preparation.

2. If perchloric acid spills, obtain new, prechilled tube.

Specimen Minimum Volume

1 mL blood added to special collection tube

Specimen Stability Information

Specimen Type Temperature Time
Whole blood Refrigerated 15 days

Reject Due To


Mild OK; Gross OK


Mild OK; Gross OK




Use of any anticoagulant other than special tube


Reference Values

0.08-0.16 mmol/L


NIH Unit

0.7-1.4 mg/dL

Day(s) and Time(s) Performed

Tuesday, Friday; Varies

CPT Code Information


LOINC Code Information

Test ID Test Order Name Order LOINC Value
PYR Pyruvic Acid, B In Process


Result ID Test Result Name Result LOINC Value
8657 Pyruvic Acid, B 14121-8
7729 Pyruvic Acid, B 2905-8


Biochemical Genetics Patient Information (T602) in Special Instructions.

Analytic Time

6 days

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.