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Test Code ACTMN Acetaminophen Level, LAB43

Performing Laboratory

St. Luke's Hospital Cedar Rapids

Specimen Requirements

Container/Tube:

Preferred: Green-top (sodium or lithium heparin gel)

Acceptable: Gold-top serum gel tube, plain red-top tube, Lavender-top (EDTA) tube,

                      Light blue-top (sodium citrate)

Specimen Volume: 0.2 mL of plasma or serum

Collection Instructions: Peak level occur 30 to 60 minutes following an oral dose.

Note: 1. Time to steady state is 5 to 20 hours.

2. Severe liver damage can occur at levels >150 mcg/mL at 4 hours post ingestion, or 50 mcg/mL after 12 hours. Antidotes are available but need to be administered within 8 to 10 hours after overdose.

Reference Values

Therapeutic range: 10-20 mcg/mL

Critical value: ≥150 mcg/mL

Useful For

Acetaminophen (brand name: Tylenol®) levels are measured to determine concentrations in the blood stream.  This can be of extreme importance in cases of suspected intoxication because effective antidotes are available.

Day(s) Test Set Up

Monday through Sunday

Methodology

Colorimetric

Test Classification and CPT Coding

80329