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Test Code ACTMN Acetaminophen Level, LAB43



Performing Laboratory

St. Luke's Hospital Cedar Rapids

Specimen Requirements


Preferred: Green-top (sodium or lithium heparin gel)

Acceptable: Gold-top serum gel tube, plain red-top tube, Lavender-top (EDTA) tube,

                      Light blue-top (sodium citrate)

Specimen Volume: 0.2 mL of plasma or serum

Collection Instructions: Peak level occur 30 to 60 minutes following an oral dose.

Note: 1. Time to steady state is 5 to 20 hours.

2. Severe liver damage can occur at levels >150 mcg/mL at 4 hours post ingestion, or 50 mcg/mL after 12 hours. Antidotes are available but need to be administered within 8 to 10 hours after overdose.

Reference Values

Therapeutic range: 10-20 mcg/mL

Critical value: ≥150 mcg/mL

Day(s) Test Set Up

Monday through Sunday

Test Classification and CPT Coding


Useful For

Acetaminophen (brand name: Tylenol®) levels are measured to determine concentrations in the blood stream.  This can be of extreme importance in cases of suspected intoxication because effective antidotes are available.