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Test Code E2 Estradiol, Serum, LAB523

Performing Laboratory

St. Luke's Hospital, Cedar Rapids

Specimen Requirements

Container/Tube:

 

Preferred: Green top (Lithium Heparin)

Acceptable:  Red-top serum, Gold top serum

Specimen: 0.5 mL

Minimum:  0.015 mL

 

Stability: 

  • Room temperature:  24 hours.  Samples on analyzer should be analyzed within 2 hrs
  • Refrigeration (2°-8°C):  48 hours
  • Frozen (≤ -20°C): 6 months.  Freeze samples only once and mix thoroughly after thawing. 

 

Transport Temperature: Refrigerated 

Reference Values

 

Male (pg/mL)

Female (pg/mL)

1-10 Years

<5-20

6-27

18+ Years

11-43

 

Follicular phase

 

31-90

Ovulation phase

 

60-533

Luteal phase

 

60-232

Post-menopausal

 

154-3243

Pregnancy: 1st Trimester

 

1561-21280

Pregnancy: 2nd Trimester

 

8525->30000

Pregnancy: 3rd Trimester

 

<5-138

Day(s) Test Set Up

Monday-Sunday

Useful For

Elevated estradiol levels in females may also result from primary or secondary ovarian hyperfunction.  Very high estradiol levels are found during the induction of ovulation1 for assisted reproduction therapy or in pregnancy. Decreased estradiol levels in females may result from either the lack of ovarian synthesis (primary ovarian hypofunction and menopause) or a lesion in the hypothalamus-pituitary axis (secondary ovarian hypofunction). Estradiol levels are normally low in males. Elevated estradiol levels in males may be due to increased aromatization of androgens, resulting in gynecomastia.

Methodology

Immunoenzymatic Chemiluminescent Assay

Test Classification and CPT Coding

82670

Analytic Time

Stat 1 hr within receipt

Routine 2 hrs within receipt