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Test Code HOMOCY Homocysteine, LAB93


Competitive Immunoassay

Performing Laboratory

St. Luke's Hospital Cedar Rapids

Specimen Requirements


Preferred: Lavender-top (EDTA) tube

Acceptable: Green-top (lithium heparin) tube

Specimen Volume: 0.5ml of plasma

Stability: Separated specimens should be analyzed immediately or kept at 2 – 8°C for

                seven days. For longer storage, samples may be frozen at -20°C for up to three

                months if they are frozen within 24 hours.

Transport Temperature: Refrigerate
Collection Instructions: Fasting (4 hour preferred). Immediately place specimen on wet ice.

                                         If there is a delay in transport of >1 hour, spin down, separate plasma

                                         from cells, and send 0.4 mL (minimum volume: 0.15 mL) of plasma



Reference Values

Adults: 3.2-10.7 µmol/L


Reference values apply to fasting specimens only.

Day(s) Test Set Up

Monday through Sunday

Test Classification and CPT Coding


Useful For

Homocysteine levels are useful in the diagnosis of homocysteinuria which can be caused by decreased levels of Folic acid, vitamin B6 and vitamin B12.

Hyperhomocysteinemia was found to be associated with an increased risk for ischemic heart disease, stroke, peripheral arterial disease and deep venous thrombosis, as well as for neural tube defects and preeclampsia in pregnancy.