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Test Code PFA Platelet Function Analysis, Blood, LAB318


Platelet Function Assay (PFA) Analyzer

Performing Laboratory

St. Luke's Hospital Cedar Rapids

Specimen Requirements



Preferred: Light blue-top (sodium citrate) tube
Specimen Volume:  TWO full 2 mL tubes of sodium citrate whole blood

Transport Temperature: Ambient

Collection Instructions: Do not centrifuge. Forward promptly.

TWO Na Citrate anticoagulated blood (blue top) tubes.  Phlebotomist must draw at least 2 mL of blood in each large plastic tube for accurate determination. 


Specimen must arrive within 4 hours of draw. Do not use mechanical mixers. Specimens must not be transported through the pneumatic tube system.

Reference Values

COL/EPI: 74-171 seconds

COL/ADP: 44-114 seconds

Day(s) Test Set Up

Monday through Sunday

Test Classification and CPT Coding


Useful For

The most common causes of platelet dysfunction are related to uremia, von Willebrand disease (vWD), and exposure to aspirin or aspirin like agents or non-steroidal anti-inflammatory drugs (NSAIDS). The Collagen/Epinephrine Cartridge is used to detect platelet dysfunction induced by intrinsic platelet defects, vWD, functional deficiencies or exposure to platelet inhibiting agents.  The Collagen/ADP Cartridge is used for subsequent testing to determine if an abnormal result with the COL/EPI Cartridge was caused by the effect of Acetylsalicylic acid (ASA) or medications containing ASA or NSAIDS.