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Test Code PROCLT Procalcitonin, LAB2677

Performing Laboratory

St. Luke's Hospital Cedar Rapids

Specimen Requirements

Container/Tube: 

Preferred: Green-top lithium heparin tube

Acceptable: Gold-top serum gel tube or plain red-top tube, EDTA plasma (see Note)

Minimum Volume:  18 uL plus dead volume

Stability:  Stable for 24 hours at room temperature, refrigerate up to 48 hours.  For prolonged storage, freeze samples up to 12 months.

 

Reference Values

 

PCT Level

Interpretation

≤ 0.50 ng/mL

Systemic infection (sepsis) is not likely.  Local bacterial infection is possible.

> 0.51 to ≤ 2.00 ng/mL

Systemic infection (sepsis) is possible, but other conditions are known to elevate PCT as well.

> 2.00 ng/mL

Systemic infection (sepsis) is likely, unless other causes are known.

≥ 10.00 ng/mL

Important systemic inflammatory response, almost exclusively due to severe bacterial sepsis or septic shock.

 

Early (<6 hours) or localized infections may not show significant procalcitonin elevations.  Elevations in procalcitonin may be seen in settings other than bacterial infection, including major trauma or surgery, severe burns, and sever/prolonged cardiogenic shock or organ hypoperfusion.

 

Neonates <2 ng/mL at birth, rises to ≤20 ng/mL at 18 to 30 hours, then falls to adult level by 72 hours.

Day(s) Test Set Up

Monday through Sunday

Useful For

Procalcitonin is useful in the detection of bacterial infections as well as in determining the risk of severe sepsis in patients.

Methodology

Sandwich Electrochemiluminesence

Test Classification and CPT Coding

84145

Report Available

STAT within 1 hour of receipt

Routine within 2 hours of receipt