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Test Code GENTP Gentamicin Level Peak, LAB28

Performing Laboratory

St. Luke's Hospital Cedar Rapids

Specimen Requirements

 

Container/Tube:

Preferred:  Mint green-top (lithium heparin) tube

Acceptable:  Serum, Li-heparin, Na-heparin, or Na-EDTA plasma

Specimen Volume:  A minimum sample volume of 1.3 µL plus a dead volume is required for testing.

Stability:   Samples are stable for 1 week at 2-8 ⁰C or 4 weeks at -15 to -25 ⁰C. S

 

Collection Instructions: Peak level should be drawn 1 hour post dose (intramuscular) or 30 to 60 minutes post dose (intravenous).  Specimens should not be drawn or stored in glass.

Note: Gentamicin time to steady state is after 2.5 to 75 hours of chronic dosing.

 

Reference Values

Therapeutic range: 5-8 mcg/mL

Critical value: >12 mcg/mL

Day(s) Test Set Up

Monday through Sunday

Useful For

Gentamicin is an aminoglycoside antibiotic which exhibits high potency and a broad spectrum bacterial action against both gram-negative and gram-positive organisms.  It exhibits a narrow therapeutic index which makes its use hazardous, especially in patients with impaired renal function.

Methodology

Enzyme Immunoassay

Test Classification and CPT Coding

80170

Report Available

STAT within 1 hour of receipt

Routine within 2 hours of receipt