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Test Code HCGQNT HCG, Quantitative, Pregnancy, LAB143

Performing Laboratory

St. Luke's Hospital Cedar Rapids

Specimen Requirements

Container/Tube:

Preferred: Green-top (lithium heparin) tube

Acceptable: Gold-top serum gel tube, plain red-top tube, EDTA plasma

Minimum Specimen Volume: 6 µL plus a dead volume

Stability: Sample should be kept at 2 – 8 °C and analyzed within 14 days. Sample is stable for 5 days at 20‑25 °C.  For longer storage, samples may be frozen at -20 °C for 12 months.  Freeze only once.

Collection Instructions:

Note: 1. biotin effects this assay
           2. Even though this test is sometimes used to follow the course of therapy for tumors, no β-                     HCG method has been approved by the FDA for use as a tumor marker.

 

 

 

Reference Values

Non–pregnant, premenopausal women

<5mIU/mL

Females, >62 years (Post-menopausal)

≤7 mIU/mL

Adult males

<2 mIU/mL

 

Approximate Gestational

Age (weeks)

Approximate hCG

Range (mIU/mL)

2 – 4

39 – 8388

5 – 6

861 – 88,769

6 – 8

8636 – 218,085

8 – 10

18,700 – 244,467

10 – 12

23,143 – 181,899

13 – 27

6303 – 97,171

28 – 49

4360 – 74,883

Day(s) Test Set Up

Monday through Sunday

Useful For

The hormone is an excellent marker for pregnancy. Healthy, non-pregnant individuals have low
(<5 mIU/mL) to undetectable hCG in serum. During pregnancy, hCG concentrations increase as noted above and then show a gradual decrease after the first trimester. Unusually low or rapidly declining levels may indicate an abnormal condition such as an ectopic pregnancy or impending spontaneous abortion.

Methodology

Chemiluminescence

Test Classification and CPT Coding

84702

Report Available

STAT within 1 hour of receipt. Routine within 2 hours of receipt.