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Test Code ITRMM Itraconazole, Serum

Additional Codes

MAYO Test ID

ITCON

EPIC Test ID

LAB2567

Reporting Name

Itraconazole, S

Useful For

Verifying systemic absorption of orally administered itraconazole

 

Patients with life-threatening fungal infections

 

Patients considered at risk for poor absorption or rapid clearance of itraconazole

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Specimen Type

Serum Red


Specimen Required


Supplies: Sarstedt Aliquot Tube, 5 mL (T914)

Collection Container/Tube:

Preferred: Red top (serum gel/SST are not acceptable)

Acceptable: None

Submission Container/Tube: Plastic vial

Specimen Volume: 1 mL

Collection Instructions: Within 2 hours of collection, centrifuge and aliquot serum into a plastic vial.


Specimen Minimum Volume

0.18 mL

Specimen Stability Information

Specimen Type Temperature Time
Serum Red Refrigerated (preferred) 29 days
  Ambient  29 days
  Frozen  29 days

Reference Values

ITRACONAZOLE (TROUGH):

>0.5 mcg/mL (localized infection)

>1 mcg/mL (systemic infection)

 

HYDROXYITRACONAZOLE:

Hydroxyitraconazole is an active metabolite; no defined therapeutic range has been established.

Day(s) Performed

Monday through Friday; Saturday

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.

CPT Code Information

80189

LOINC Code Information

Test ID Test Order Name Order LOINC Value
ITCON Itraconazole, S 10989-2

 

Result ID Test Result Name Result LOINC Value
81247 Itraconazole, S 10989-2
5122 Hydroxyitraconazole 18337-6

Report Available

1 to 3 days

Reject Due To

Gross hemolysis OK
Gross lipemia OK
Gross icterus OK

Method Name

Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS)

Forms

If not ordering electronically, complete, print, and send a Therapeutics Test Request (T831) with the specimen.