Test Code PANCAM Cytoplasmic Neutrophil Antibodies, Serum
Additional Codes
MAYO Test ID |
ANCA |
EPIC Test ID |
LAB458 |
Reporting Name
Cytoplasmic Neutrophilic Ab, SUseful For
Evaluating patients with clinical features of ANCA-associated vasculitis, specifically granulomatosus with polyangiitis, microscopic polyangiitis, and eosinophilic granulomatosus with polyangiitis
Performing Laboratory
Mayo Clinic Laboratories in RochesterSpecimen Type
SerumAdditional Testing Requirements
When used for diagnosis, it is recommended that specific tests for proteinase 3 antibodies and myeloperoxidase antibodies be performed first, with additional testing for anti-neutrophil cytoplasmic antibodies only needed in certain circumstances.(3) A testing algorithm based on these recommendations is available. For more information see VASC / Antineutrophil Cytoplasmic Antibodies Vasculitis Panel, Serum.
Specimen Required
Supplies: Sarstedt Aliquot Tube, 5 mL (T914)
Collection Container/Tube:
Preferred: Serum gel
Acceptable: Red top
Submission Container/Tube: Plastic vial
Specimen Volume: 0.8 mL
Collection Instructions: Centrifuge and aliquot serum into plastic vial.
Specimen Minimum Volume
0.4 mL
Specimen Stability Information
Specimen Type | Temperature | Time | Special Container |
---|---|---|---|
Serum | Refrigerated (preferred) | 21 days | |
Frozen | 21 days |
Reference Values
<1:4 (Negative)
Day(s) Performed
Monday through Saturday
Test Classification
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.CPT Code Information
86036 x2
86037-Titer (if appropriate)
LOINC Code Information
Test ID | Test Order Name | Order LOINC Value |
---|---|---|
ANCA | Cytoplasmic Neutrophilic Ab, S | 87427-1 |
Result ID | Test Result Name | Result LOINC Value |
---|---|---|
3114 | c-ANCA | In Process |
3119 | p-ANCA | 17357-5 |
Report Available
3 to 4 daysReject Due To
Gross hemolysis | Reject |
Gross lipemia | Reject |
Gross icterus | OK |
Heat-treated specimen | Reject |
Method Name
Indirect Immunofluorescence (IIF)
Forms
If not ordering electronically, complete, print, and send 1 of the following forms with the specimen:
-General Request (T239)
-Renal Diagnostics Test Request (T830)
Testing Algorithm
For more information see:
-First-Line Screening for Autoimmune Liver Disease Algorithm.