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Test Code SALIC Salicylate Level, LAB34



Performing Laboratory

St. Luke's Hospital Cedar Rapids

Specimen Requirements


Preferred: Green-top (lithium heparin) tube

Acceptable: Gold-top serum gel tube or plain red-top tube

Specimen Volume: 0.2 mL of plasma or serum

Stability: Separated specimens should be analyzed immediately or kept at room temperature

               for 7 days or 2 – 8 °C and analyzed within 2 weeks. For longer storage, samples may

               be frozen at -20 °C for up to 6 months.

Collection Instructions: Peak level for salicylic acid occurs 1 to 2 hours after a dose.

Note: 1. Time to steady state for salicylic acid is after 5 to 7 days of chronic oral dosing. Half-life

               for salicylic acid is 3 hours after a single 250 mg dose, or up to 20 hours for higher doses.

          2. There is no antidote to salicylic acid toxicity.



Reference Values

Analgesic therapeutic range: 2-10 mg/dL

Antiarthritic therapeutic range: 15-30 mg/dL

Critical value: >30 mg/dL

Day(s) Test Set Up

Monday through Sunday

Test Classification and CPT Coding


Useful For

Salicylate measurements are used in the diagnosis and treatment of salicylate overdose and in monitoring salicylate levels to insure appropriate therapy. The salicylates are a group of compounds used as analgesics, antipyretics and anti-inflammatory agents.  Acetylsalicylic acid (aspirin), the most commonly used salicylate, and sodium salicylate are the principal compounds taken orally.