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Test Code VANCO Vancomycin, Random, LAB40

Performing Laboratory

St. Luke's Hospital Cedar Rapids

Specimen Requirements


Preferred: Green-top (lithium heparin) tube

Acceptable: Gold-top serum gel tube or plain red-top tube

Specimen Volume: 0.2 mL of lithium heparin plasma

Stability: Separated specimens should be analyzed immediately or kept at 2 – 8 °C

               and analyzed within 72 hours. For longer storage, samples may be frozen at -20 °C

               for up to 6 months.

Collection Instructions: Random vancomycin level should be ordered when patient is on 1

               dose per day therapy.

Note: 1. Vancomycin time to steady state is after 20 to 30 hours of chronic dosing.

          2. Levels may be ordered any time toxicity is suspected.


Reference Values

No established reference values

Day(s) Test Set Up

Monday through Sunday

Analytic Time

STAT within 1 hour of receipt. Routine within 2 hours of receipt.

Useful For

Vancomycin is a glycopeptide antibiotic, which is bactericidal against many gram-positive and some gram-negative cocci. It is useful in therapy of severe staphylococcal (including methicillin-resistant staphylococci) infections in patients who cannot receive or who have failed to respond to the penicillins and cephalosporins.


Strong correlations have been shown between serum levels of vancomycin and both therapeutic effect and toxicity in specific patient types.


Turbidimetric Inhibition Immunoassay

Test Classification and CPT Coding